The CRML is a state-of-the-art 15,000 square-foot research facility that houses an interdisciplinary team of biomedical engineers, electrophysiologists, physicians and veterinarians. Each year, approximately 400,000 people in North America die of cardiac arrhythmias. CRML research seeks to understand the formation, maintenance and termination of life-threatening cardiac arrhythmias with the goal of improving treatment strategies.
CRML's primary objective is to investigate the causes and potential treatments of cardiac arrhythmias. To accomplish this objective, CRML researchers obtain large amounts of electrophysiologic data from various modalities, or data sources.
Among others, these data sources include a 528-channel electrical mapping system, an optical mapping system using CCD cameras, and cardiac MRI. Analysing and visualising this data requires significant image and signal processing techniques, coupled with advanced graphical capabilities. According to R. Kyle Justice, a CRML programmer/analyst: "We needed a software package that would facilitate both qualitative and quantitative understanding of the mechanisms of arrhythmias. We needed powerful software that combined advanced visualisation tools with heavy-duty number-crunching functionality."
CRML's search for a data visualisation solution led them to PV-WAVE, the flagship product from Visual Numerics Inc. PV-WAVE is an open environment for developing and deploying Visual Data Analysis (VDA) applications that help customers turn raw data into meaningful information. These VDA applications let users visualise and manipulate complex or very large data sets to detect and display patterns, trends, anomalies, and other vital information.
PV-WAVE includes hundreds of mathematical and statistical analysis routines from Visual Numerics? IMSL Numerical Libraries, as well as image processing, signal processing, mapping, and general data manipulation features. Engineers, scientists, business analysts, and software developers access this robust and extensive set of functions through an array-oriented programming language. PV-WAVE also includes advanced graphical user interface development tools that facilitate the construction of intuitive front-ends, making the product's functionality easily accessible to others in an organisation.
Mr. Justice cites increased productivity as the leading benefit of using PV-WAVE. "It significantly reduces our development time, which makes everyone more productive", Mr. Justice said. "We rarely have exact specifications for a particular piece of software that we need. The software tends to grow right along with the research. PV-WAVE is perfect for this interactive, dynamic process because of its flexible programming environment. We need everything from small and large-scale applications to "on the fly" command-line programming. And from time to time, we need to call external C programmes, which is a snap with PV-WAVE."
In addition to PV-WAVE's flexibility, Mr. Justice also likes the software's ease-of-use and cross-platform portability. "GUI-development is quite easy using the built-in Wave Widgets", he said. "In addition, the cross-platform compatibility of PV-WAVE makes life a lot easier for us. We have Sun and SGI workstations as well as PCs running Linux and Windows. Our programmes run seamlessly on all of these platforms 99 percent of the time."
Mr. Justice added that he is "excited" about the new VTK capabilities available in PV-WAVE 7.5, the latest version of the software released in August 2001. The Visualisation ToolKit (VTK) is an open source, freely available software system developed by Clifton Park, New York-based Kitware Inc., that provides 3D graphics, image processing, and advanced visualisation techniques using OpenGL.
Included in PV-WAVE 7.5 are more than two dozen new functions that allow access to Kitware's VTK, both at a high-level for ease-of-use, and through low-level routines that facilitate the creation of more complex, specialised visualisations. With the 7.5 release, PV-WAVE will provide the high-level 3D interactive visualisation techniques commonly associated with OpenGL without burdening its users with having to learn hundreds of low-level commands. The integration of VTK into PV-WAVE provides the optimum solution. PV-WAVE users are now able to produce accelerated graphics in their applications without having to learn a new programming paradigm or understand the intricacies of OpenGL.
PV-WAVE is available for many popular operating systems: Windows 98, Windows 2000/NT, Unix (Sun, HP, SGI, Compaq & IBM), and Linux. Windows and Linux pricing starts at $1,795. Unix pricing starts at $3,995.