The Human Liver Proteome Project (HLPP) is backed by an initial round of $16 million in funding from the Chinese government for a three-year pilot study to be completed in 2005. The effort was launched in May 2004 and is aimed at setting up the collaborations, standards, and procedures for tallying the thousands of proteins expressed in human liver cells. So far, 79 labs, 37 of them in China, have signed on to the liver proteome effort.
Scientists rely on the computational power of the SGI Altix system, installed in September 2004, to conduct analytical and biochemical research on liver samples in an attempt to identify links between diseases and protein changes. The shared-memory capabilities of the Altix system are particularly useful to researchers whose detailed analysis on multiple samples can generate 25GB of data every day, resulting in up to 20TB of data a year.
"A problem of this magnitude is extremely challenging. That's why we selected the SGI solution", stated Mr. Yun Ping Zhu, director of Gene and Protein Research Group. "The scalability architecture, high-bandwidth and shared-memory capabilities of the SGI solution make it possible to compute and manage the massive amounts of data needed to conduct protein research of this magnitude. To meet our requirements for large data management, we use an SGI SAN solution with more than 40TB storage capability and CXFS shared filesystem for easy access to all our data."
"Every year, liver diseases kill hundreds of thousands of people in China. We are excited that China Human Proteome Organisation, one of the top life science research organisations, is using SGI technology for their leading-edge liver research", stated Alex Lee, president, SGI China. "For more than two decades, SGI core competencies of HPC, storage and visualization have been keenly aligned with the development of life sciences in the world and have helped in accelerating research progress, fueling innovation and discovery in many disciplines. We believe this unique combination of SGI technology and life science leading scientists will ultimately lead to faster and more successful life science research in China."
"SGI helps scientific and creative customers solve the world's most complex computational problems. These customers want the highest performing platform, which is what an Intel Itanium 2-based computing system provides", stated Lim, Sang Chong, director of Enterprises Platform Group, Asia Pacific, Intel. The solution includes an SGI Altix 3000 supercomputer powered by 32 Intel Itanium 2 processors and running the Linux operating system, SGI SAN solution and SGI InfiniteStorage Shared Filesystem CXFS, with two TP9300 storage devices, with more than 40TB storage capability.
China Human Proteome Organisation is led by Dr. FuChu He, research fellow of China Academy of Science. This is a research organisation across 37 labs in China, it is funded by Ministry of Science and Technology and China Academy of Science.